Optical Wireless Data Center Networks

Bandwidth and computation-intensive Big Data applications in disciplines like social media, bio- and nano-informatics, Internet-of-Things (IoT), and real-time analytics, are pushing existing access and core (backbone) networks as well as Data Center Networks (DCNs) to their limits. Next generation DCNs must support continuously increasing network traffic while satisfying minimum performance requirements of latency, reliability, flexibility and scalability. Therefore, a larger number of cables (i.e., copper-cables and fiber optics) may be required in conventional wired DCNs. In addition to limiting the possible topologies, large number of cables may result into design and development problems related to wire ducting and maintenance, heat dissipation, and power consumption. To address the cabling complexity in wired DCNs, we propose OWCells, a class of optical wireless cellular data center network architectures in which fixed line of sight (LOS) optical wireless communication (OWC) links are used to connect the racks arranged in regular polygonal topologies. We present the OWCell DCN architecture, develop its theoretical underpinnings, and investigate routing protocols and OWC transceiver design. To realize a fully wireless DCN, servers in racks must also be connected using OWC links. There is, however, a difficulty of connecting multiple adjacent network components, such as servers in a rack, using point-to-point LOS links. To overcome this problem, we propose and validate the feasibility of an FSO-Bus to connect multiple adjacent network components using NLOS point-to-point OWC links. Finally, to complete the design of the OWC transceiver, we develop a new class of strictly and rearrangeably non-blocking multicast optical switches in which multicast is performed efficiently at the physical optical (lower) layer rather than upper layers (e.g., application layer). Advisors: Jitender S. Deogun and Dennis R. Alexande

Wireless Communication in Data Centers: A Survey

Data centers (DCs) is becoming increasingly an integral part of the computing infrastructures of most enterprises. Therefore, the concept of DC networks (DCNs) is receiving an increased attention in the network research community. Most DCNs deployed today can be classified as wired DCNs as copper and optical fiber cables are used for intra- and inter-rack connections in the network. Despite recent advances, wired DCNs face two inevitable problems; cabling complexity and hotspots. To address these problems, recent research works suggest the incorporation of wireless communication technology into DCNs. Wireless links can be used to either augment conventional wired DCNs, or to realize a pure wireless DCN. As the design spectrum of DCs broadens, so does the need for a clear classification to differentiate various design options. In this paper, we analyze the free space optical (FSO) communication and the 60 GHz radio frequency (RF), the two key candidate technologies for implementing wireless links in DCNs. We present a generic classification scheme that can be used to classify current and future DCNs based on the communication technology used in the network. The proposed classification is then used to review and summarize major research in this area. We also discuss open questions and future research directions in the area of wireless DCs

Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London

Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study

Background: Surgical site infection (SSI) is one of the most common infections associated with health care, but its importance as a global health priority is not fully understood. We quantified the burden of SSI after gastrointestinal surgery in countries in all parts of the world. Methods: This international, prospective, multicentre cohort study included consecutive patients undergoing elective or emergency gastrointestinal resection within 2-week time periods at any health-care facility in any country. Countries with participating centres were stratified into high-income, middle-income, and low-income groups according to the UN's Human Development Index (HDI). Data variables from the GlobalSurg 1 study and other studies that have been found to affect the likelihood of SSI were entered into risk adjustment models. The primary outcome measure was the 30-day SSI incidence (defined by US Centers for Disease Control and Prevention criteria for superficial and deep incisional SSI). Relationships with explanatory variables were examined using Bayesian multilevel logistic regression models. This trial is registered with ClinicalTrials.gov, number NCT02662231. Findings: Between Jan 4, 2016, and July 31, 2016, 13 265 records were submitted for analysis. 12 539 patients from 343 hospitals in 66 countries were included. 7339 (58·5%) patient were from high-HDI countries (193 hospitals in 30 countries), 3918 (31·2%) patients were from middle-HDI countries (82 hospitals in 18 countries), and 1282 (10·2%) patients were from low-HDI countries (68 hospitals in 18 countries). In total, 1538 (12·3%) patients had SSI within 30 days of surgery. The incidence of SSI varied between countries with high (691 [9·4%] of 7339 patients), middle (549 [14·0%] of 3918 patients), and low (298 [23·2%] of 1282) HDI (p < 0·001). The highest SSI incidence in each HDI group was after dirty surgery (102 [17·8%] of 574 patients in high-HDI countries; 74 [31·4%] of 236 patients in middle-HDI countries; 72 [39·8%] of 181 patients in low-HDI countries). Following risk factor adjustment, patients in low-HDI countries were at greatest risk of SSI (adjusted odds ratio 1·60, 95% credible interval 1·05–2·37; p=0·030). 132 (21·6%) of 610 patients with an SSI and a microbiology culture result had an infection that was resistant to the prophylactic antibiotic used. Resistant infections were detected in 49 (16·6%) of 295 patients in high-HDI countries, in 37 (19·8%) of 187 patients in middle-HDI countries, and in 46 (35·9%) of 128 patients in low-HDI countries (p < 0·001). Interpretation: Countries with a low HDI carry a disproportionately greater burden of SSI than countries with a middle or high HDI and might have higher rates of antibiotic resistance. In view of WHO recommendations on SSI prevention that highlight the absence of high-quality interventional research, urgent, pragmatic, randomised trials based in LMICs are needed to assess measures aiming to reduce this preventable complication

A Survey on Inter-Cell Interference Coordination Techniques in OFDMA-Based Cellular Networks

Orthogonal Frequency Division Multiplexing Access (OFDMA) has been increasingly deployed in various emerging and evolving cellular systems to reduce interference and improve overall system performance. However, in these systems Inter- Cell Interference (ICI) still poses a real challenge that limits the system performance, especially for users located at the cell edge. Inter-cell interference coordination (ICIC) has been investigated as an approach to alleviate the impact of interference and improve performance in OFDMA-based systems. A common ICIC technique is interference avoidance in which the allocation of the various system resources (e.g., time, frequency, and power) to users is controlled to ensure that the ICI remains within acceptable limits. This paper surveys the various ICIC avoidance schemes in the downlink of OFDMA-based cellular networks. In particular, the paper introduces new parameterized classifications and makes use of these classifications to categorize and review various static (frequency reuse-based) and dynamic (cell coordination-based) ICIC schemes

Wireless Communication in Data Centers: A Survey

Data centers (DCs) is becoming increasingly an integral part of the computing infrastructures of most enterprises. Therefore, the concept of DC networks (DCNs) is receiving an increased attention in the network research community. Most DCNs deployed today can be classified as wired DCNs as copper and optical fiber cables are used for intra- and inter-rack connections in the network. Despite recent advances, wired DCNs face two inevitable problems; cabling complexity and hotspots. To address these problems, recent research works suggest the incorporation of wireless communication technology into DCNs. Wireless links can be used to either augment conventional wired DCNs, or to realize a pure wireless DCN. As the design spectrum of DCs broadens, so does the need for a clear classification to differentiate various design options. In this paper, we analyze the free space optical (FSO) communication and the 60 GHz radio frequency (RF), the two key candidate technologies for implementing wireless links in DCNs. We present a generic classification scheme that can be used to classify current and future DCNs based on the communication technology used in the network. The proposed classification is then used to review and summarize major research in this area. We also discuss open questions and future research directions in the area of wireless DCs

Optical Wireless Data Center Networks

Bandwidth and computation-intensive Big Data applications in disciplines like social media, bio- and nano-informatics, Internet-of-Things (IoT), and real-time analytics, are pushing existing access and core (backbone) networks as well as Data Center Networks (DCNs) to their limits. Next generation DCNs must support continuously increasing network traffic while satisfying minimum performance requirements of latency, reliability, flexibility and scalability. Therefore, a larger number of cables (i.e., copper-cables and fiber optics) may be required in conventional wired DCNs. In addition to limiting the possible topologies, large number of cables may result into design and development problems related to wire ducting and maintenance, heat dissipation, and power consumption. To address the cabling complexity in wired DCNs, we propose OWCells, a class of optical wireless cellular data center network architectures in which fixed line of sight (LOS) optical wireless communication (OWC) links are used to connect the racks arranged in regular polygonal topologies. We present the OWCell DCN architecture, develop its theoretical underpinnings, and investigate routing protocols and OWC transceiver design. To realize a fully wireless DCN, servers in racks must also be connected using OWC links. There is, however, a difficulty of connecting multiple adjacent network components, such as servers in a rack, using point-to-point LOS links. To overcome this problem, we propose and validate the feasibility of an FSO-Bus to connect multiple adjacent network components using NLOS point-to-point OWC links. To complete the design of the OWC transceiver, we develop a new class of strictly and rearrangeably non-blocking multicast optical switches in which multicast is performed efficiently at the physical optical (lower) layer rather than upper layers (e.g., application layer)

Optical Wireless Data Center Networks

Bandwidth and computation-intensive Big Data applications in disciplines like social media, bio- and nano-informatics, Internet-of-Things (IoT), and real-time analytics, are pushing existing access and core (backbone) networks as well as Data Center Networks (DCNs) to their limits. Next generation DCNs must support continuously increasing network traffic while satisfying minimum performance requirements of latency, reliability, flexibility and scalability. Therefore, a larger number of cables (i.e., copper-cables and fiber optics) may be required in conventional wired DCNs. In addition to limiting the possible topologies, large number of cables may result into design and development problems related to wire ducting and maintenance, heat dissipation, and power consumption. To address the cabling complexity in wired DCNs, we propose OWCells, a class of optical wireless cellular data center network architectures in which fixed line of sight (LOS) optical wireless communication (OWC) links are used to connect the racks arranged in regular polygonal topologies. We present the OWCell DCN architecture, develop its theoretical underpinnings, and investigate routing protocols and OWC transceiver design. To realize a fully wireless DCN, servers in racks must also be connected using OWC links. There is, however, a difficulty of connecting multiple adjacent network components, such as servers in a rack, using point-to-point LOS links. To overcome this problem, we propose and validate the feasibility of an FSO-Bus to connect multiple adjacent network components using NLOS point-to-point OWC links. To complete the design of the OWC transceiver, we develop a new class of strictly and rearrangeably non-blocking multicast optical switches in which multicast is performed efficiently at the physical optical (lower) layer rather than upper layers (e.g., application layer)